The Biggest Discussions in Retina from the 2022 ASRS Annual Meeting
This past week, the American Society of Retina Specialists (ASRS) held its 40th Annual Meeting in New York City to discuss landmark data and the newest advancements in retina care.  The HCPLive team was on-site at the Javits Center in Manhattan conducting interviews with expert retina specialists on topics including drugs for neovascular age-related macular degeneration and geographic atrophy,...
14m Jul 20, 2022
14m
FDA Approves Ruxolitinib: New Horizons in Vitiligo Care
  On Monday, the US Food and Drug Administration (FDA) approved ruxolitinib cream 1.5% for the treatment of nonsegmental vitiligo in adults and pediatric patients 12 years and older, making it both the first FDA-approved therapy for repigmentation and the only topical formulation of a JAK inhibitor approved in the United States.   The groundbreaking approval was supported by phase 3 data fro...
8m Jul 20, 2022
8m
How Pegloticase Plus Methotrexate is Breaking Ground in Gout Care
Last week, the US Food and Drug Administration (FDA) approved (https://www.hcplive.com/view/fda-approves-pegloticase-plus-methotrexate-for-uncontrolled-gout) the co-treatment of pegloticase (Krystexxa) injection plus methotrexate (MTX) for uncontrolled gout, a decision bolstered by data from phase 4 of the MIRROR study.   In that study, 71% of patients who were treated with this combination t...
16m Jul 12, 2022
16m
What Ustekinumab Provides in Long-Term IBD Care
Despite a bevy of biologics available for people struggling with Crohn’s disease and ulcerative colitis (UC), not all patients are able to respond to or tolerate a vast majority of approved therapies.   Fortunately, new data presented at Digestive Disease Week (DDW) 2022 suggests that ustekinumab (STELARA) could function as an alternative option to bio-failure and bio-naïve patients living wi...
14m Jun 29, 2022
14m
Exploring New Horizons in Ophthalmology Care with Gene Therapy
If you’ve been keeping an eye on recent developments in ophthalmic care, then you’ll know that several new therapeutic agents that had been approved by the US Food and Drug Administration (FDA) in recent months, including ranibizumab delivered via Port Delivery System (PDS) and faricimab (https://www.hcplive.com/view/fda-approves-faricimab-patients-wet-amd-or-dme) , the latter of which became t...
9m Jun 27, 2022
9m
How the Newest Dupilumab Approval Solves an "Unmet Need" in Children with AD
Earlier this month, dupilumab became the first and only biologic medicine approved by the US Food and Drug Administration for the treatment of atopic dermatitis in patients of all ages, from infancy through adulthood. The approval of dupilumab as an add-on maintenance therapy for children 6 months to 5 years with moderate to severe atopic dermatitis was described as “a tremendous advancement” ...
17m Jun 20, 2022
17m
Dermatologists Discuss the FDA Approval of Baricitinib for Alopecia Areata
On June 13, the US Food and Drug Administration (FDA) approved oral baricitinib (https://www.hcplive.com/view/fda-approves-baricitinib-for-alopecia-areata) (Olumiant) tablets for the treatment of severe alopecia areata in adults, which marked the first approval of a systemic treatment for the disorder. The approval has excited patients and providers alike who struggled for decades to treat sev...
23m Jun 16, 2022
23m
Dermatologists Discuss the FDA Approval of Baricitinib for Alopecia Areata
 On June 13, the US Food and Drug Administration (FDA) approved oral baricitinib (https://www.hcplive.com/view/fda-approves-baricitinib-for-alopecia-areata) (Olumiant) tablets for the treatment of severe alopecia areata in adults, which marked the first approval of a systemic treatment for the disorder.   The approval has excited patients and providers alike who struggled for decades to treat...
22m Jun 16, 2022
22m
Sleeping Through Infectious Disease and the COVID-19 Vaccine
After presenting at the SLEEP 2022 annual meeting, Dr. Aric Prather explains the findings of his previous research demonstrated lack of sleep (6 hours or less) was associated with a 4 times higher risk of becoming sick after exposure to rhinovirus in an interview with HCPLive. Currently, Prather and his team at UCSF are working with a large naive population for a study that began in March 2021....
22m Jun 14, 2022
22m
Multi-System Approaches to Treating Pediatric Morphea
In recognition of National Scleroderma Awareness Month, HCPLive spoke with several prominent dermatologists today who addressed some of the concerns and advancements related to the rare, multi-system disease.   Scleroderma is often referred to as “morphea” by dermatologists, and the condition typically presents with the tightening and hardening of the skin. Depending on the region of the body...
9m Jun 09, 2022
9m
Roberto Simons-Linares, MD: The Importance of Bariatric Surgery
9m Jun 07, 2022
9m
Rare Disease Report: Myelodysplastic Syndromes & Acute Myeloid Leukemia
Mikkael Sekeres, MD, is no stranger to rare disease. In his own words, there are rare diseases and then there are very rare diseases. Sickle cell is a rare condition with an incidence rate of just over 100 per 100,000 people. Sekeres focuses much of his treatment on patients with bone marrow disorders like myelodysplastic syndromes (MDS) and acute myeloid leukemia (AML). These conditions have a...
23m Jun 03, 2022
23m
How Tapinarof Cream 1% is Set to Revolutionize Psoriasis Care
Last week (https://www.hcplive.com/view/fda-approves-tapinarof-cream-adults-plaque-psoriasis) , the US Food and Drug Administration approved tapinarof cream, 1% (VTAMA) for the treatment of plaque psoriasis of all severities in adult patients, ushering in the first and only FDA-approved steroid-free topical medication in its class.   Remarkably, it had been 25 years since a novel chemical ent...
24m Jun 01, 2022
24m
Improving Screening Strategies for Cardiac Sarcoidosis
In recent years, the acknowledgement of cardiac involvement in patients with sarcoidosis has become increasingly important. Thanks to advanced screening techniques, new research has suggested that approximately 2-5% of patients with sarcoidosis also struggle with cardiac sarcoidosis.   However, the practice of adding echocardiography and ambulatory ECG to standard screening with the intention...
9m May 23, 2022
9m
What's Limiting Medical Marijuana Therapy in Rheumatology?
Benjamin Nowell, PhD, and Stuart Silverman, MD, FACP, FACR, discuss the recent publication of a new review article, “Cannabis for rheumatic disease pain: A review of current literature.” Investigators discovered that progress in understanding cannabis-based therapies for treating the pain associated with rheumatic disease is hindered due to a lack of standardization of clinical research and cur...
23m May 19, 2022
23m
Improving the Availability of COVID-19 Therapeutics in Vulnerable Communities
Beyond vaccination, what are some methods for treating COVID-19 in both inpatient and outpatient settings? In the 2 years since the beginning of the pandemic, the strategies for protecting people from this deadly virus have certainly evolved, yet questions remain regarding COVID-19 therapeutics and their availability in certain communities and during times of scarcity.   For this episode of D...
16m May 12, 2022
16m
A Medical Volunteer at the Ukraine-Poland Refugee Border
Today's episode features Selena S. Li, MD, a Massachusetts General Hospital surgery resident, who recently traveled overseas with a volunteer medical group to provide treatments and care to refugees escaping the Russian invasion. For more clinical news and expert interviews, visit us at HCPLive.com. (https://hcplive.com/) To learn more about donating to or volunteering with Medical Volunteers...
12m May 09, 2022
12m
New Methods for Overcoming Environmental and Food Allergies
When it comes to allergies, the number of affected individuals in the United States alone is staggering. Approximately 20 million adults and 6 million children in the US are affected by seasonal allergies, and roughly 32 million Americans struggle with a myriad of food allergies.   Seasonal allergies have been front-of-mind for many Americans, especially with the Spring season in full effect....
12m May 04, 2022
12m
Evaluating the Efficacy of Faricimab in Patients with DME from Underrepresented Communities
The newly approved ophthalmic drug faricimab (Vabysmo) has already made waves by being the first of its drug class to be approved for both diabetic macular edema (DME) and neovascular age-related degeneration (nAMD). A new phase 4 clinical trial from Genentech seeks to expand on the efficacy of the drug in patients with DME from underrepresented populations. The efficacy and safety of faricim...
14m May 02, 2022
14m
Rare Disease Report: TANGO2
In this hallmark episode, we discuss a condition that has only been documented in 70 cases worldwide. Dr. Amelle Shilligton is a clinical geneticist at Cincinnati Children's Hospital Medical Center. In this conversation, Ashley and Jacob Wiley share the story of how they rushed their 15 month old daughter Aislynn to that hospital, and Dr. Shillington explains how she eventually solved the myst...
32m Apr 28, 2022
32m
How Determi-Nation Promotes Diversity in Psoriatic Research and Treatment
When addressing psoriatic disease, it is important to consider how it uniquely affects people with skin of color. People from different racial and ethnic groups often struggle with psoriatic disease due to delays in diagnosis, misdiagnosis, and limited access to diagnostic testing and treatment. Furthermore, the lack of access to care and treatment has resulted in biologic use being 69% lower ...
17m Apr 28, 2022
17m
NAFLD Prevalence Increasing in Pediatric Patients
Last week, a new investigation (https://www.hcplive.com/view/vos-md-future-research-pediatric-nafld) confirmed a higher prevalence of non-alcoholic fatty liver disease (NAFLD) in pediatric patients than previously thought.   The data was part of the ongoing observational study called TARGET-NASH, which included participants with NAFLD and/or alcoholic steatohepatitis (NASH).   The study, wh...
9m Apr 26, 2022
9m
Approximately 9 Million More Americans Exposed to Air Pollution in 2022
Today, the American Lung Association released the 23rd annual “State of the Air” report, which detailed the nationwide exposure to ozone and particle pollution in the United States in 2022. The new report revealed that approximately 9 million more people were affected by particle pollution since last year’s report, with more reported days with “very unhealthy” and “hazardous” air quality than ...
23m Apr 20, 2022
23m
How JAK Inhibitors Revolutionized Dermatology Care
Last summer, Derm Discussions host Brad Glick, DO, invited Brett King, MD, PhD, Yale School of Medicine, to the program to discuss an emerging class of dermatology therapy known as Janus kinase (JAK) inhibitors. At the time, small molecule drugs such as upadacitinib (Rinvoq) were approved for the treatment of conditions like rheumatoid arthritis and ulcerative colitis. Since then, updacacitin...
14m Apr 19, 2022
14m
Exploring New Possibilities in Vitiligo Therapy
An estimated 2 million patients in the United States have vitiligo, which is a dermatologic condition defined by depigmentation of the skin.   Though there is currently no cure, recent medical advancements have helped patients and providers alike gain a broader perspective on the skin condition. Likewise, prominent cultural figures with vitiligo have also contributed addressing the stigma sur...
11m Apr 19, 2022
11m
Addressing Rising Insomnia Rates in the United States
Last week, the Alliance for Sleep committee announced new data from the largest sleep-based survey in the US, which found that 70% of people with trouble sleeping due to insomnia were “desperate to find a solution”. Insomnia affects approximately 25 million adults in the US, and is partially responsible for the roughly $7 billion spent annually on products or sleep aids such as blackout curtai...
15m Apr 11, 2022
15m
Overdrive Podcast: ArthritisPower Redesign and Research
Dr. Benjamin Nowell and David Curtis chat about the the recent press release that CreakyJoints published addressing updates to their ArthritisPower interface in order to improve the user’s experience, including incorporating patient perspectives. They discuss how the changes will help both patients and rheumatologists alike, recent research, and what we have to look forward to in the near futur...
20m Apr 11, 2022
20m
Introducing Insulin Therapy and Dietary Care to Patients with Diabetes
As diabetes care continues to evolve, especially in regard to insulin therapies, so too must the conversations being had between patients and doctors. Fortunately, a recent webinar titled “Institutional Perspectives in Diabetes: New Advances in Insulin Therapy for the Management of Type 2 Diabetes” hosted a myriad of thoughtful discussions regarding the importance of insulin therapies for diab...
23m Apr 06, 2022
23m
Diagnosing and Treating Rosacea : An Overview
April is Rosacea Awareness Month! While the cause of rosacea is still unknown, what is known is that it is estimated to affect up to 16 million people in the United States alone.   Additionally, a recent survey by the National Rosacea Society indicated that 47% of affect patients were unaware of the disorder prior to their diagnosis, and 95% stated that they knew very little about the signs ...
11m Apr 04, 2022
11m
Ardythe Morrow, PhD: The Connection Between Gut Bacteria and Psychiatric Disorders
18m Mar 29, 2022
18m
Why Dermatologists Diagnose Psoriasis Less in Black Patients
Coming live from the American Academy of Dermatology (AAD) 2022 Meeting in Boston, managing editor Kevin Kunzmann sits down with investigators from University of Perelman School of Medicine to discuss new data showing disparities in psoriasis diagnoses by race, and how dermatologists can become more confident in identifying new cases.
13m Mar 26, 2022
13m
Rare Disease Report: Relapsing Polychondritis
For Autoimmune Disease Awareness Month, Joe Ahearn, MD, discusses relapsing polychondritis from a clinical perspective with Michael Linn, an advocate and the Vice Chair of the Relapsing Polychondritis Foundation. The team shares an exciting announcement about the partnership they've formed.
24m Mar 25, 2022
24m
Improving Racial and Ethnic Representation in Pediatric Trials
Representation of different racial and ethnic groups in clinical trials has been an ongoing concern across all clinical fields, and pediatrics is no exception.   A recent study from Emory University School of Medicine found that the number of pediatric clinical trials that reported participant race and ethnicity had increased from 2011 to 2020. However, participant race and ethnicity were sti...
10m Mar 24, 2022
10m
How Dermatologists Combat Misinformation on Social Media
In recent years, the subject of misinformation has pervaded many of our conversations regarding world news, politics and more. But how might it affect dermatology care, especially in the realm of social media?   A recent study (https://www.hcplive.com/view/acne-related-social-media-content-lacking-in-dermatologist-input) from the University of California found that among 439 acne-related post...
12m Mar 17, 2022
12m
The Promise of FT218 Therapy for Narcolepsy Patients
How has sleep (https://www.hcplive.com/clinical/sleep) medicine changed in recent years, and what does the future hold? These are questions that are being asked this week at the World Sleep 2022 congress in Rome, Italy, and new data presented at the conference by Avadel Pharmaceuticals could provide a answers for patients struggling from narcolepsy. A new post-hoc analyses for the sodium oxyba...
9m Mar 15, 2022
9m
Overdrive Update: Guselkumab for Treating Active Psoriatic Arthritis Part 2
On this month’s episode, Soumya D. Chakravarty, MD, PhD, discusses the growing body of clinical evidence evaluating joint efficacy, safety and patient-reported outcomes in patients with psoriatic arthritis receiving guselkumab.
15m Mar 14, 2022
15m
Revising the CDC Clinical Guideline for Prescribing Opioids
The CDC proposed new clinical practice guidelines for prescribing opioids for pain management. (https://www.hcplive.com/clinical/pain) These guidelines are not yet official as the government has opened the docket to obtain comments from the public regarding the proposed guidelines. While the purpose of the guideline is to serve as a clinical tool for providers, the recommendations are voluntar...
24m Mar 10, 2022
24m
Championing Women in Health Care
 Today is International Women’s Day, a global holiday officially recognized by the United Nations in 1975 with historical significance reaching as far back as the early 1900s.   It’s a day that celebrates the cultural, political, and socioeconomic accomplishments of women worldwide. For this episode of , DocTalk will be celebrating women in the healthcare system with Dr. Heather Brandling-Ben...
11m Mar 08, 2022
11m
Defining and Managing Sarcoidosis in African American Patients
Sarcoidosis is a systemic inflammatory disease of unknown origin that is categorized by the formulation of granulomas in various parts of the body including the lungs, skin, heart, and brain.   Though the disease does not always require medication, careful monitoring and management is always recommended as it may present in fatigue, pain, small fiber neuropathy and other comorbidities.   Sa...
20m Mar 02, 2022
20m
Rare Disease Report: Adrenomyeloneuropathy & Gene Therapy
Our first episode back features Karen Kozarsky, PhD, an expert on gene therapy and adrenomyeloneuropathy (AMN). She has an in-depth discussion with our new host Giuliana Grossi about what the future might hold for AMN treatment.
30m Feb 28, 2022
30m
Improving the Healthcare System for African American Patients
At HCPLive, we’ve had the incredible privilege of speaking with doctors from a variety of different clinical fields as well as different cultural, racial, and ethnic backgrounds. Without their dedication, insights, and generosity, the health care system and the world at large would be at a loss.    Even publications such as our own benefit from their work in a myriad of ways. In this episode ...
14m Feb 24, 2022
14m
Efficacy of Guselkumab for Treating Psoriatic Arthritis
Rheumatology Network interviewed Terence Rooney, MD, to discuss the findings of a Network Meta-Analysis that examined the efficacy of guselkumab (TREMFYA) for skin clearance and joint improvements in patients with psoriatic arthritis.
16m Feb 23, 2022
16m
Improving Telemedicine for Black Patients with Heart Disease
Across all areas of study in health care and especially in recent years, African American patients and physicians have experienced racial inequity regarding telemedicine practices across the US.    However, a new pilot trial (https://www.hcplive.com/view/reaching-black-patients-heart-disease-study-benefit-texting-versus-online-portals) from the Perelman School of Medicine at the University of...
16m Feb 21, 2022
16m
How Rheumatology Patients Should Be Vaccinated for COVID-19
In early February, the American College of Rheumatology (ACR) announced (https://www.hcplive.com/view/acr-updates-covid-19-vaccine-guidance--fourth-doses-recommendations) an updated version of its COVID-19 Vaccine Clinical Guidance for Patients with Rheumatic and Musculoskeletal Diseases. (https://www.rheumatology.org/Portals/0/Files/COVID-19-Vaccine-Clinical-Guidance-Rheumatic-Diseases-Summary...
15m Feb 16, 2022
15m
An Interplay Between Solutions and Success In Physician Burnout with Janae Sharp
In this episode of DocTalk, we interview Janae Sharp, founder of the Sharp index, on some of these larger, slightly philosophical questions surrounding physician burnout, including how to measure and define success, as well as the deeper layers of stigma that must be addressed as part of the process.
27m Feb 15, 2022
27m
The Cultural and Clinical Challenges of Sickle Cell with Ifeyinwa “Ify” Osunkwo, MD
Though sickle cell disease (https://www.hcplive.com/clinical/sickle-cell) had been present in Africa for over 5000 years, it was first “discovered” in 1910 when a dental student named Walter Clement Noel became the first patient to be formally diagnosed. From there, more would be uncovered about the disease in the decades following his diagnosis, such as how it disproportionately affects patien...
20m Feb 09, 2022
20m
Examining Pediatric Myocarditis Risk with COVID-19 Vaccination with Matthew E. Oster, MD, MPH
In late January, a team of investigators from the Centers for Disease Control and Prevention (CDC) reported findings (https://www.hcplive.com/view/young-men-adolescents-raised-risk-covid-19-mrna-vaccine-myocarditis) from the Vaccine Adverse Event Reporting System (VAERS) indicating a significantly low risk of myocarditis following vaccination with either available messenger RNA (mRNA) vaccine f...
13m Feb 07, 2022
13m
Addressing Gender Inequality in the Medical Field with Marcia Klein-Patel, MD
Today marks the fourth-ever National Women Physicians Day, an event that that is intended to pay respect to women physicians across the country. It’s held each year on Elizabeth Blackwell's birthday, who was the first female medical doctor in the United States.   Though much has changed since then, there are still fewer female doctors nationally than male doctors, an issue often caused by gend...
10m Feb 02, 2022
10m
Guselkumab Ranked Highest Overall in Skin Clearance with Philip Mease, MD
Last week, Janssen announced results (https://www.hcplive.com/view/guselkumab-ranked-highest-skin-clearance-psoriatic-arthritis) from a network meta-analysis (NMA) that showed that the biologic therapy guselkumab ranked highest for overall level of skin clearance. The NMA involved 33 phase 3 randomized clinical trials and 15 different targeted therapies including risakinumab and more. Philip J...
19m Jan 31, 2022
19m
Physician Burnout Reaching Critical Levels During COVID-19 with Lakshmana Swamy, MD, MBA
Prior to the COVID-19 (https://www.hcplive.com/clinical/coronavirus) pandemic, the subject of physician burnout was likely not considered or completely understood by large swaths of the American public. Despite this, burnout has been an issue that has plagued physicians for decades prior to the pandemic, and the consequences of it are far-reaching.   In an interview for the latest installment...
13m Jan 26, 2022
13m