808e9326-1751-4154-a778-cefeca685554/5-0
00:00:03.344 --> 00:00:06.470
fan of Endeavor Health.
He is the Associate Chief Science Officer.

808e9326-1751-4154-a778-cefeca685554/5-1
00:00:06.470 --> 00:00:08.664
Brian,
thank you so much for joining us today.

808e9326-1751-4154-a778-cefeca685554/6-0
00:00:09.304 --> 00:00:10.744
Thank you for inviting me.

808e9326-1751-4154-a778-cefeca685554/8-0
00:00:11.304 --> 00:00:15.319
So for those who don't know,
Endeavor Health is a health system based

808e9326-1751-4154-a778-cefeca685554/8-1
00:00:15.319 --> 00:00:18.876
in Evanston, Illinois,
just outside of Chicago, with about 2,

808e9326-1751-4154-a778-cefeca685554/8-2
00:00:18.876 --> 00:00:23.179
000 hospital beds across 9 hospitals
served by 10,000 providers. So Brian,

808e9326-1751-4154-a778-cefeca685554/8-3
00:00:23.179 --> 00:00:27.883
as the Associate Chief Science Officer,
I'm sure you have a lot of things on your

808e9326-1751-4154-a778-cefeca685554/8-4
00:00:27.883 --> 00:00:30.636
plate.
Today we're going to talk about clinical

808e9326-1751-4154-a778-cefeca685554/8-5
00:00:30.636 --> 00:00:31.784
trials, specifically

808e9326-1751-4154-a778-cefeca685554/9-0
00:00:32.344 --> 00:00:37.038
how you're working to improve access to
clinical trials and the latest treatments

808e9326-1751-4154-a778-cefeca685554/9-1
00:00:37.038 --> 00:00:41.561
outside of major medical centers in major
cities. So I'll hand it over to you.

808e9326-1751-4154-a778-cefeca685554/9-2
00:00:41.561 --> 00:00:44.824
What's going on with clinical trials at
Endeavor Health?

808e9326-1751-4154-a778-cefeca685554/10-0
00:00:45.904 --> 00:00:52.613
Yeah, so we're in a really unique area.
And I think our issues are uniform really

808e9326-1751-4154-a778-cefeca685554/10-1
00:00:52.613 --> 00:00:58.340
throughout a lot of the country.
We're in Chicago, it's a major city.

808e9326-1751-4154-a778-cefeca685554/10-2
00:00:58.340 --> 00:01:04.885
We are part of eight different academic
institutions in Chicago. And, you know,

808e9326-1751-4154-a778-cefeca685554/10-3
00:01:04.885 --> 00:01:09.304
it's finding our footprint and remaining
competitive.

808e9326-1751-4154-a778-cefeca685554/12-0
00:01:10.264 --> 00:01:16.514
We personally are part of a large network
that, you know, as you said,

808e9326-1751-4154-a778-cefeca685554/12-1
00:01:16.514 --> 00:01:22.853
we have 9 hospitals in our system.
We continue to expand. We service 4.

808e9326-1751-4154-a778-cefeca685554/12-2
00:01:22.853 --> 00:01:28.047
1 million patients.
And so how do you keep patients in the

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00:01:28.047 --> 00:01:28.664
system?

808e9326-1751-4154-a778-cefeca685554/13-0
00:01:29.064 --> 00:01:36.584
How do you use clinical trials as one of
those main attractions that not only

808e9326-1751-4154-a778-cefeca685554/14-0
00:01:38.104 --> 00:01:42.739
gives the care that I think patients
deserve, but also, you know,

808e9326-1751-4154-a778-cefeca685554/14-1
00:01:42.739 --> 00:01:47.865
attracts patients and from a, you know,
kind of a business minded sense,

808e9326-1751-4154-a778-cefeca685554/14-2
00:01:47.865 --> 00:01:53.624
how are we retaining that and not losing
those patients to other sites where they

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00:01:53.624 --> 00:01:56.784
believe may have different trials,
different

808e9326-1751-4154-a778-cefeca685554/15-0
00:01:56.904 --> 00:02:02.522
you know, technologies, et cetera.
So that's really where clinical trial

808e9326-1751-4154-a778-cefeca685554/15-1
00:02:02.522 --> 00:02:02.984
space.

808e9326-1751-4154-a778-cefeca685554/16-0
00:02:04.624 --> 00:02:10.472
is we want to and certainly have proven
ourselves that we have the ability to

808e9326-1751-4154-a778-cefeca685554/16-1
00:02:10.472 --> 00:02:15.570
offer clinical trials of latest,
greatest care to on top of already

808e9326-1751-4154-a778-cefeca685554/16-2
00:02:15.570 --> 00:02:19.544
outstanding care throughout a large
hospital system.

808e9326-1751-4154-a778-cefeca685554/17-0
00:02:20.424 --> 00:02:23.379
Got it.
So let's go with a concrete use case,

808e9326-1751-4154-a778-cefeca685554/17-1
00:02:23.379 --> 00:02:28.775
if you wouldn't mind. Walking us through.
Now, I don't want to put you on the spot,

808e9326-1751-4154-a778-cefeca685554/17-2
00:02:28.775 --> 00:02:32.950
so I'll give you a choice.
Either patient Jayne has some kind of

808e9326-1751-4154-a778-cefeca685554/17-3
00:02:32.950 --> 00:02:37.640
condition and the only treatment
available for this maybe orphan disease

808e9326-1751-4154-a778-cefeca685554/17-4
00:02:37.640 --> 00:02:41.944
is through a clinical trial being offered
through Endeavor Health.

808e9326-1751-4154-a778-cefeca685554/18-0
00:02:42.304 --> 00:02:46.992
That might be a good place to start.
Or starting in the story of how Endeavor

808e9326-1751-4154-a778-cefeca685554/18-1
00:02:46.992 --> 00:02:51.921
Health is leveraging clinical trials to
improve access and maintain market share.

808e9326-1751-4154-a778-cefeca685554/18-2
00:02:51.921 --> 00:02:53.304
Leave it in your hands.

808e9326-1751-4154-a778-cefeca685554/19-0
00:02:54.104 --> 00:02:59.211
Yeah, I think both,
we can talk about both of those because I

808e9326-1751-4154-a778-cefeca685554/19-1
00:02:59.211 --> 00:03:04.648
think they're both very relevant.
You know, I do think, you know,

808e9326-1751-4154-a778-cefeca685554/19-2
00:03:04.648 --> 00:03:09.673
we have 10,000 providers.
Most of us are fellowship trained,

808e9326-1751-4154-a778-cefeca685554/19-3
00:03:09.673 --> 00:03:14.616
really top of the game,
have believed that the best care is

808e9326-1751-4154-a778-cefeca685554/19-4
00:03:14.616 --> 00:03:16.264
constantly evolving.

808e9326-1751-4154-a778-cefeca685554/20-0
00:03:16.744 --> 00:03:20.546
And as you start really pushing that
envelope, you know,

808e9326-1751-4154-a778-cefeca685554/20-1
00:03:20.546 --> 00:03:23.815
you move quickly into that clinical trial
space,

808e9326-1751-4154-a778-cefeca685554/20-2
00:03:23.815 --> 00:03:28.819
because that's really going to test and
offer the latest cares. Sometimes,

808e9326-1751-4154-a778-cefeca685554/20-3
00:03:28.819 --> 00:03:32.888
as you brought up,
as compassionate care in certain oncology

808e9326-1751-4154-a778-cefeca685554/20-4
00:03:32.888 --> 00:03:35.624
cases, which I'll give you an example of,

808e9326-1751-4154-a778-cefeca685554/21-0
00:03:36.824 --> 00:03:39.795
to give access to treatments that,
you know,

808e9326-1751-4154-a778-cefeca685554/21-1
00:03:39.795 --> 00:03:43.955
patients would not otherwise have access
to. And so, you know,

808e9326-1751-4154-a778-cefeca685554/21-2
00:03:43.955 --> 00:03:48.577
even in a real world example,
and certainly trials that I have either

808e9326-1751-4154-a778-cefeca685554/21-3
00:03:48.577 --> 00:03:53.132
witnessed or have been part of,
cancer trials are the lowest hanging

808e9326-1751-4154-a778-cefeca685554/21-4
00:03:53.132 --> 00:03:56.104
fruit there because they're the most
common.

808e9326-1751-4154-a778-cefeca685554/22-0
00:03:56.184 --> 00:04:02.005
common because of that space is always
pushing to hopefully stomp out cancer one

808e9326-1751-4154-a778-cefeca685554/22-1
00:04:02.005 --> 00:04:05.958
day. But also,
whether I'm talking about cancer trials

808e9326-1751-4154-a778-cefeca685554/22-2
00:04:05.958 --> 00:04:09.624
or I'm talking about other even benign
conditions,

808e9326-1751-4154-a778-cefeca685554/23-0
00:04:10.664 --> 00:04:15.576
ranging from psychiatry to ophthalmology
to urology.

808e9326-1751-4154-a778-cefeca685554/23-1
00:04:15.576 --> 00:04:20.118
There are so many clinical trials in that
space.

808e9326-1751-4154-a778-cefeca685554/23-2
00:04:20.118 --> 00:04:27.069
But if you're going to use a concrete
example, and specifically, you know,

808e9326-1751-4154-a778-cefeca685554/23-3
00:04:27.069 --> 00:04:31.704
you have a patient,
he's a 74 year old gentleman,

808e9326-1751-4154-a778-cefeca685554/24-0
00:04:32.104 --> 00:04:39.097
who has a advanced prostate cancer. And,
you know, he has gone through for many,

808e9326-1751-4154-a778-cefeca685554/24-1
00:04:39.097 --> 00:04:45.917
many years a lot of the traditional
therapies that have involved testosterone,

808e9326-1751-4154-a778-cefeca685554/24-2
00:04:45.917 --> 00:04:51.184
wiping agents out.
And once you go through so many different

808e9326-1751-4154-a778-cefeca685554/26-0
00:04:51.304 --> 00:04:54.962
you know, treatments,
you kind of come to an end.

808e9326-1751-4154-a778-cefeca685554/26-1
00:04:54.962 --> 00:05:00.157
There's not a lot of new things that you
can offer. And as an example,

808e9326-1751-4154-a778-cefeca685554/25-0
00:04:57.104 --> 00:04:57.584
Mhm.

808e9326-1751-4154-a778-cefeca685554/26-2
00:05:00.157 --> 00:05:06.083
he was offered a clinical trial to look
at several different things. Number one,

808e9326-1751-4154-a778-cefeca685554/26-3
00:05:06.083 --> 00:05:11.864
he was able to get the most advanced
imaging. So that is on trial to say, hey,

808e9326-1751-4154-a778-cefeca685554/27-0
00:05:12.184 --> 00:05:16.706
we can locate that tumor with the latest,
greatest, you know,

808e9326-1751-4154-a778-cefeca685554/27-1
00:05:16.706 --> 00:05:21.738
kind of radio tracers in that field and
really localize that cancer.

808e9326-1751-4154-a778-cefeca685554/27-2
00:05:21.738 --> 00:05:26.041
And because it's a new radiotherapy or
imaging technology,

808e9326-1751-4154-a778-cefeca685554/27-3
00:05:26.041 --> 00:05:31.730
you can really leverage that to really
localize that where the disease is and

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00:05:31.730 --> 00:05:35.304
hopefully come up with treatments based
on that.

808e9326-1751-4154-a778-cefeca685554/28-0
00:05:35.784 --> 00:05:41.260
And then he was so happy with that result.
And based on that radio tracer,

808e9326-1751-4154-a778-cefeca685554/28-1
00:05:41.260 --> 00:05:46.810
he was actually able to enroll in a
different trial that tagged a radiation

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00:05:46.810 --> 00:05:51.921
therapy to that imaging agent.
So that would target and localize that

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00:05:51.921 --> 00:05:56.667
treatment that much better.
And so that's the kind of thing that

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00:05:56.667 --> 00:05:57.544
we're really

808e9326-1751-4154-a778-cefeca685554/29-0
00:05:57.864 --> 00:06:02.591
aiming for is to say that, hey,
these are not standard of care,

808e9326-1751-4154-a778-cefeca685554/29-1
00:06:02.591 --> 00:06:08.206
but all of the trials that we enroll
patients in have that ability to offer

808e9326-1751-4154-a778-cefeca685554/29-2
00:06:08.206 --> 00:06:13.155
benefits to that patient,
even though that they're not widely used

808e9326-1751-4154-a778-cefeca685554/29-3
00:06:13.155 --> 00:06:16.184
or certainly in guidelines at that point.

808e9326-1751-4154-a778-cefeca685554/30-0
00:06:16.904 --> 00:06:18.984
But it, but it improves the.

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00:06:19.944 --> 00:06:25.130
patient care and access,
and certainly the quality of care that

808e9326-1751-4154-a778-cefeca685554/31-1
00:06:25.130 --> 00:06:26.184
patients get.

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00:06:27.064 --> 00:06:30.995
So other than joining podcasts like this
one,

808e9326-1751-4154-a778-cefeca685554/32-1
00:06:30.995 --> 00:06:37.747
you mentioned that clinical trial of the
kind you just described help increase

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00:06:37.747 --> 00:06:42.961
patient enrollment.
How is Endeavor leveraging its abilities

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00:06:42.961 --> 00:06:47.064
to identify the appropriate clinical
trials for

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00:06:48.024 --> 00:06:52.589
for eligible populations in order to
increase patient enrollment and general

808e9326-1751-4154-a778-cefeca685554/33-1
00:06:52.589 --> 00:06:56.087
market share. Of course,
I guess the market share would be

808e9326-1751-4154-a778-cefeca685554/33-2
00:06:56.087 --> 00:07:00.771
primarily for the target sick populations,
but if there's any kind of tertiary

808e9326-1751-4154-a778-cefeca685554/33-3
00:07:00.771 --> 00:07:04.744
benefits to well populations,
that might also be worth mentioning.

808e9326-1751-4154-a778-cefeca685554/34-0
00:07:05.984 --> 00:07:08.504
Yeah, so I mean, I, we...

808e9326-1751-4154-a778-cefeca685554/36-0
00:07:09.584 --> 00:07:13.804
Endeavor Health has changed names
throughout time,

808e9326-1751-4154-a778-cefeca685554/36-1
00:07:13.804 --> 00:07:20.424
but historically was Evanston Healthcare,
a much smaller operation back over 20

808e9326-1751-4154-a778-cefeca685554/36-2
00:07:20.424 --> 00:07:24.562
years ago.
But it was one of the first systems to

808e9326-1751-4154-a778-cefeca685554/35-0
00:07:22.864 --> 00:07:23.464
Mhm.

808e9326-1751-4154-a778-cefeca685554/36-3
00:07:24.562 --> 00:07:30.024
employ an electronic health record system
or EHR system. In fact,

808e9326-1751-4154-a778-cefeca685554/38-0
00:07:30.104 --> 00:07:35.784
We were the beta testing site for the
most common thing known as Epic.

808e9326-1751-4154-a778-cefeca685554/38-1
00:07:35.784 --> 00:07:40.984
And so Epic has evolved and certainly we
have data on, you know,

808e9326-1751-4154-a778-cefeca685554/38-2
00:07:40.984 --> 00:07:46.184
millions of patients for over 20 years.
And as that has evolved,

808e9326-1751-4154-a778-cefeca685554/37-0
00:07:44.584 --> 00:07:44.744
Mm.

808e9326-1751-4154-a778-cefeca685554/38-3
00:07:46.184 --> 00:07:52.824
we have been forward thinking to say, hey,
we want to be able to overlay different

808e9326-1751-4154-a778-cefeca685554/38-4
00:07:52.824 --> 00:07:53.624
electronic

808e9326-1751-4154-a778-cefeca685554/39-0
00:07:54.304 --> 00:08:01.300
programs so that we can quickly search
patients for eligibility in clinical

808e9326-1751-4154-a778-cefeca685554/39-1
00:08:01.300 --> 00:08:07.652
trials and to enhance and identify those
patients who would qualify.

808e9326-1751-4154-a778-cefeca685554/39-2
00:08:07.652 --> 00:08:12.624
So we have that ability to look at one of
the largest

808e9326-1751-4154-a778-cefeca685554/41-0
00:08:12.904 --> 00:08:19.224
healthcare systems in the country and
really quickly identify patients.

808e9326-1751-4154-a778-cefeca685554/41-1
00:08:19.224 --> 00:08:25.280
And that's pertinent because a lot of
trials can benefit the masses,

808e9326-1751-4154-a778-cefeca685554/41-2
00:08:25.280 --> 00:08:31.864
but there are certain trials that are
really designed for rare conditions.

808e9326-1751-4154-a778-cefeca685554/42-0
00:08:32.184 --> 00:08:37.605
And so one of those issues has been that
we haven't been able to identify those

808e9326-1751-4154-a778-cefeca685554/40-0
00:08:32.784 --> 00:08:32.984
Mm.

808e9326-1751-4154-a778-cefeca685554/42-1
00:08:37.605 --> 00:08:41.671
patients historically,
but with these type of technologies,

808e9326-1751-4154-a778-cefeca685554/42-2
00:08:41.671 --> 00:08:46.957
we're identifying those patients with the
rare conditions and getting them in

808e9326-1751-4154-a778-cefeca685554/42-3
00:08:46.957 --> 00:08:48.584
trials or offering them.

808e9326-1751-4154-a778-cefeca685554/43-0
00:08:47.944 --> 00:08:52.418
Just to jump in for one second, Brian,
because I want to clarify so our

808e9326-1751-4154-a778-cefeca685554/43-1
00:08:52.418 --> 00:08:56.396
listeners understand.
You're saying that maybe there's only 50,

808e9326-1751-4154-a778-cefeca685554/43-2
00:08:56.396 --> 00:09:00.746
000 Americans with condition Y,
and maybe they're not all in Chicago,

808e9326-1751-4154-a778-cefeca685554/43-3
00:09:00.746 --> 00:09:03.543
maybe some are in Texas or Maine or
Florida,

808e9326-1751-4154-a778-cefeca685554/43-4
00:09:03.543 --> 00:09:06.464
and it just so happens that the
biotherapeutic

808e9326-1751-4154-a778-cefeca685554/44-0
00:09:06.624 --> 00:09:11.987
intervention that would treat condition Y
is being offered through Endeavor and

808e9326-1751-4154-a778-cefeca685554/44-1
00:09:11.987 --> 00:09:15.608
nowhere else,
how do you find these patients that are

808e9326-1751-4154-a778-cefeca685554/44-2
00:09:15.608 --> 00:09:21.173
not Endeavor patients but are across the
country and bring them in to enroll them?

808e9326-1751-4154-a778-cefeca685554/44-3
00:09:21.173 --> 00:09:25.464
Because in order to get approval by the
FDA, you need a certain

808e9326-1751-4154-a778-cefeca685554/45-0
00:09:25.544 --> 00:09:29.235
kind of amount of participation and
you're needing to identify these patients.

808e9326-1751-4154-a778-cefeca685554/45-1
00:09:29.235 --> 00:09:30.824
Is that what you're talking about?

808e9326-1751-4154-a778-cefeca685554/46-0
00:09:31.384 --> 00:09:36.298
Yeah, I mean, it goes both ways.
It goes locally, right? Because we have 4.

808e9326-1751-4154-a778-cefeca685554/46-1
00:09:36.298 --> 00:09:41.665
1 million patients to now in our data set
to query on an annual basis and look for

808e9326-1751-4154-a778-cefeca685554/46-2
00:09:41.665 --> 00:09:46.774
people who would qualify for, you know,
rare conditions and common conditions.

808e9326-1751-4154-a778-cefeca685554/46-3
00:09:46.774 --> 00:09:51.624
But we also have partnered through many
different organizations, networks,

808e9326-1751-4154-a778-cefeca685554/47-0
00:09:51.824 --> 00:09:56.900
but they're all electronically linked to
a help identify patients, you know,

808e9326-1751-4154-a778-cefeca685554/47-1
00:09:56.900 --> 00:10:00.461
kind of quicker.
And a lot of this is really when you

808e9326-1751-4154-a778-cefeca685554/47-2
00:10:00.461 --> 00:10:01.384
start looking.

808e9326-1751-4154-a778-cefeca685554/48-0
00:10:01.664 --> 00:10:01.864
Um...

808e9326-1751-4154-a778-cefeca685554/50-0
00:10:03.624 --> 00:10:08.799
in this type of space is in the oncology
realm, the neuroscience realm,

808e9326-1751-4154-a778-cefeca685554/50-1
00:10:08.799 --> 00:10:14.261
where a lot of the conditions and
treatments may be more rare. So it again,

808e9326-1751-4154-a778-cefeca685554/50-2
00:10:14.261 --> 00:10:20.011
has the ability to look nationwide to
look for eligible patients. But you know,

808e9326-1751-4154-a778-cefeca685554/49-0
00:10:16.944 --> 00:10:17.544
Mhm.

808e9326-1751-4154-a778-cefeca685554/50-3
00:10:20.011 --> 00:10:22.024
a lot of this is also posted

808e9326-1751-4154-a778-cefeca685554/53-0
00:10:22.904 --> 00:10:29.354
on trial sites and government sites to
make people aware and practitioners aware.

808e9326-1751-4154-a778-cefeca685554/53-1
00:10:29.354 --> 00:10:35.175
But really, especially internally,
when certain conditions are being met,

808e9326-1751-4154-a778-cefeca685554/53-2
00:10:35.175 --> 00:10:41.389
there will be flags that pop up that can
help identify those patients and make

808e9326-1751-4154-a778-cefeca685554/52-0
00:10:35.944 --> 00:10:36.424
Mhm.

808e9326-1751-4154-a778-cefeca685554/53-3
00:10:41.389 --> 00:10:41.704
them

808e9326-1751-4154-a778-cefeca685554/55-0
00:10:41.864 --> 00:10:45.112
provider,
the current person who's taking care of

808e9326-1751-4154-a778-cefeca685554/55-1
00:10:45.112 --> 00:10:48.231
that patient aware, so that they can,
you know,

808e9326-1751-4154-a778-cefeca685554/54-0
00:10:46.064 --> 00:10:46.544
Mmh.

808e9326-1751-4154-a778-cefeca685554/55-2
00:10:48.231 --> 00:10:52.584
refer to that trial or at least get that
patient more information.

808e9326-1751-4154-a778-cefeca685554/56-0
00:10:53.064 --> 00:10:57.056
So obviously,
Epic Care Everywhere is one way to try to

808e9326-1751-4154-a778-cefeca685554/56-1
00:10:57.056 --> 00:11:00.976
access different instances of Epic across
the country.

808e9326-1751-4154-a778-cefeca685554/56-2
00:11:00.976 --> 00:11:06.394
Does Endeavor leverage connectivity to
national networks in order to try to

808e9326-1751-4154-a778-cefeca685554/56-3
00:11:06.394 --> 00:11:12.026
identify patients with certain diagnoses
codes that might be eligible for this

808e9326-1751-4154-a778-cefeca685554/56-4
00:11:12.026 --> 00:11:13.024
sort of trial?

808e9326-1751-4154-a778-cefeca685554/57-0
00:11:14.264 --> 00:11:18.546
A lot is in motion.
So nationally becomes a little bit more

808e9326-1751-4154-a778-cefeca685554/57-1
00:11:18.546 --> 00:11:23.186
of a problem, if you will,
just because of HIPAA and things like

808e9326-1751-4154-a778-cefeca685554/57-2
00:11:23.186 --> 00:11:28.325
that. But really through the connectivity,
whether that's through Epic,

808e9326-1751-4154-a778-cefeca685554/57-3
00:11:28.325 --> 00:11:33.464
whether that's through, you know,
kind of organizations, whether that's

808e9326-1751-4154-a778-cefeca685554/60-0
00:11:33.664 --> 00:11:39.777
the American Cancer Society, the NIH,
all of that, we are part of all of those,

808e9326-1751-4154-a778-cefeca685554/60-1
00:11:39.777 --> 00:11:44.744
you know, kind of trials.
And certainly the awareness of that is

808e9326-1751-4154-a778-cefeca685554/60-2
00:11:44.744 --> 00:11:50.552
made possible through that. You know,
I think we have a much higher success

808e9326-1751-4154-a778-cefeca685554/58-0
00:11:47.064 --> 00:11:47.624
Mmh.

808e9326-1751-4154-a778-cefeca685554/60-3
00:11:50.552 --> 00:11:54.984
rate because when you control the
dialogue in the system,

808e9326-1751-4154-a778-cefeca685554/59-0
00:11:55.264 --> 00:11:55.864
Mhm.

808e9326-1751-4154-a778-cefeca685554/61-0
00:11:55.704 --> 00:11:59.263
It makes people more aware.
And so while nationally,

808e9326-1751-4154-a778-cefeca685554/61-1
00:11:59.263 --> 00:12:03.695
there's a huge presence,
and certainly we have patients coming in

808e9326-1751-4154-a778-cefeca685554/61-2
00:12:03.695 --> 00:12:08.127
all the time from other parts of the
country for clinical trials,

808e9326-1751-4154-a778-cefeca685554/61-3
00:12:08.127 --> 00:12:11.551
certainly the identification,
if just being frank,

808e9326-1751-4154-a778-cefeca685554/61-4
00:12:11.551 --> 00:12:16.722
is currently still emphasized within our
own expanded network throughout the

808e9326-1751-4154-a778-cefeca685554/61-5
00:12:16.722 --> 00:12:17.864
Chicagoland area.

808e9326-1751-4154-a778-cefeca685554/62-0
00:12:18.824 --> 00:12:22.680
So, it's my understanding, Brian,
that in 2025,

808e9326-1751-4154-a778-cefeca685554/62-1
00:12:22.680 --> 00:12:28.705
Endeavor Health had 550 active trials
across multiple specialties and 2300

808e9326-1751-4154-a778-cefeca685554/62-2
00:12:28.705 --> 00:12:34.329
clinical trial patients that were
enrolled in those trials last year.

808e9326-1751-4154-a778-cefeca685554/62-3
00:12:34.329 --> 00:12:37.864
Given the complexity and the vast volume
of

808e9326-1751-4154-a778-cefeca685554/63-0
00:12:38.024 --> 00:12:43.228
patients and trials and details,
I imagine that there's a lot of data to

808e9326-1751-4154-a778-cefeca685554/63-1
00:12:43.228 --> 00:12:46.366
orchestrate.
Are there any data challenges?

808e9326-1751-4154-a778-cefeca685554/63-2
00:12:46.366 --> 00:12:51.071
I'm asking this, of course,
because this is Healthy Data podcast.

808e9326-1751-4154-a778-cefeca685554/63-3
00:12:51.071 --> 00:12:56.490
Are there any data challenges associated
with managing such a vast array of

808e9326-1751-4154-a778-cefeca685554/63-4
00:12:56.490 --> 00:12:58.344
differing data sources and

808e9326-1751-4154-a778-cefeca685554/64-0
00:12:58.904 --> 00:13:00.184
Problems you're trying to address.

808e9326-1751-4154-a778-cefeca685554/65-0
00:13:01.224 --> 00:13:06.040
Yeah, so, you know, the amount of data,
these are big data, you know, issues.

808e9326-1751-4154-a778-cefeca685554/65-1
00:13:06.040 --> 00:13:10.980
And that's awesome because what you're
really reflecting on is that we have the

808e9326-1751-4154-a778-cefeca685554/65-2
00:13:10.980 --> 00:13:14.129
ability,
whether we're talking about genetic data,

808e9326-1751-4154-a778-cefeca685554/65-3
00:13:14.129 --> 00:13:17.278
whether we're talking about large
population data,

808e9326-1751-4154-a778-cefeca685554/65-4
00:13:17.278 --> 00:13:22.032
and all of the imaging and all the lab
work and all the patient demographics

808e9326-1751-4154-a778-cefeca685554/65-5
00:13:22.032 --> 00:13:23.144
that go into that,

808e9326-1751-4154-a778-cefeca685554/66-0
00:13:23.504 --> 00:13:27.798
This is big data there.
For every patient in a trial,

808e9326-1751-4154-a778-cefeca685554/66-1
00:13:27.798 --> 00:13:33.762
we estimate that there's over a million
data points that we are constantly

808e9326-1751-4154-a778-cefeca685554/66-2
00:13:33.762 --> 00:13:40.441
collecting. And that may even be a small,
you know, data, you know, clinical trial.

808e9326-1751-4154-a778-cefeca685554/66-3
00:13:40.441 --> 00:13:43.304
So, you know, that requires a lot of

808e9326-1751-4154-a778-cefeca685554/67-0
00:13:43.344 --> 00:13:48.090
backup of data,
and that requires a lot of secure servers,

808e9326-1751-4154-a778-cefeca685554/67-1
00:13:48.090 --> 00:13:53.077
especially in today's era,
where we're always concerned about

808e9326-1751-4154-a778-cefeca685554/67-2
00:13:53.077 --> 00:13:58.547
information and protection at all points.
And so we have, you know,

808e9326-1751-4154-a778-cefeca685554/67-3
00:13:58.547 --> 00:14:04.741
certainly huge servers that are all,
you know, kind of constantly monitored.

808e9326-1751-4154-a778-cefeca685554/67-4
00:14:04.741 --> 00:14:05.144
And I

808e9326-1751-4154-a778-cefeca685554/69-0
00:14:05.624 --> 00:14:11.166
Don't know the details of it,
because I joke that our system is very

808e9326-1751-4154-a778-cefeca685554/69-1
00:14:11.166 --> 00:14:17.754
much like Fort Knox. It's very hard to,
you know, kind of compromise that system.

808e9326-1751-4154-a778-cefeca685554/69-2
00:14:17.754 --> 00:14:23.296
But certainly all of the necessary
systems are in place, the clouds,

808e9326-1751-4154-a778-cefeca685554/69-3
00:14:23.296 --> 00:14:25.064
to really gather that.

808e9326-1751-4154-a778-cefeca685554/68-0
00:14:23.624 --> 00:14:24.104
Mhm.

808e9326-1751-4154-a778-cefeca685554/70-0
00:14:25.144 --> 00:14:25.504
Data.

808e9326-1751-4154-a778-cefeca685554/71-0
00:14:26.344 --> 00:14:31.263
Right. You know, it's another topic,
and I guess leveraging the last few

808e9326-1751-4154-a778-cefeca685554/71-1
00:14:31.263 --> 00:14:35.373
minutes of this podcast,
I know that one of your goals is to

808e9326-1751-4154-a778-cefeca685554/71-2
00:14:35.373 --> 00:14:39.416
increase access to clinical trials
outside of major cities.

808e9326-1751-4154-a778-cefeca685554/71-3
00:14:39.416 --> 00:14:43.526
So outside of Chicago,
you're trying to look to get a larger

808e9326-1751-4154-a778-cefeca685554/71-4
00:14:43.526 --> 00:14:47.434
catchment area.
You're looking to reduce barriers to care

808e9326-1751-4154-a778-cefeca685554/71-5
00:14:47.434 --> 00:14:47.704
with

808e9326-1751-4154-a778-cefeca685554/72-0
00:14:47.824 --> 00:14:53.863
transportation or hotels or food and
expand the footprint of Endeavor beyond

808e9326-1751-4154-a778-cefeca685554/72-1
00:14:53.863 --> 00:14:59.197
the immediate Chicago area.
Can you elaborate on what you're trying

808e9326-1751-4154-a778-cefeca685554/72-2
00:14:59.197 --> 00:15:04.373
to do and how data may,
kind of what new data sources or what new

808e9326-1751-4154-a778-cefeca685554/72-3
00:15:04.373 --> 00:15:05.864
data challenges are

808e9326-1751-4154-a778-cefeca685554/73-0
00:15:07.064 --> 00:15:09.464
related to those initiatives.

808e9326-1751-4154-a778-cefeca685554/74-0
00:15:10.824 --> 00:15:15.205
So in a classic model,
and something that we initially had to

808e9326-1751-4154-a778-cefeca685554/74-1
00:15:15.205 --> 00:15:18.597
overcome,
is that if you have a clinical trial,

808e9326-1751-4154-a778-cefeca685554/74-2
00:15:18.597 --> 00:15:21.777
you have that patient come into your
clinic,

808e9326-1751-4154-a778-cefeca685554/74-3
00:15:21.777 --> 00:15:26.300
they often have to come in multiple times
throughout the study.

808e9326-1751-4154-a778-cefeca685554/74-4
00:15:26.300 --> 00:15:29.904
You have to have labs drawn, evaluated,
et cetera.

808e9326-1751-4154-a778-cefeca685554/76-0
00:15:30.184 --> 00:15:35.286
And so that for a lot of patients was a
barrier because that just travel time

808e9326-1751-4154-a778-cefeca685554/76-1
00:15:35.286 --> 00:15:40.127
alone, people didn't want to, you know,
sign up for trials because it was

808e9326-1751-4154-a778-cefeca685554/76-2
00:15:40.127 --> 00:15:44.641
considered a burden. And so, you know,
certainly locally into the 4.

808e9326-1751-4154-a778-cefeca685554/76-3
00:15:44.641 --> 00:15:49.352
1 million lives that we serve,
that we've overcome that because we have

808e9326-1751-4154-a778-cefeca685554/75-0
00:15:46.824 --> 00:15:47.384
Okay.

808e9326-1751-4154-a778-cefeca685554/76-4
00:15:49.352 --> 00:15:50.464
so many different

808e9326-1751-4154-a778-cefeca685554/79-0
00:15:50.664 --> 00:15:54.089
you know,
locations throughout a large system where

808e9326-1751-4154-a778-cefeca685554/79-1
00:15:54.089 --> 00:15:58.238
patients can enroll.
So even if you live in X part of Chicago,

808e9326-1751-4154-a778-cefeca685554/79-2
00:15:58.238 --> 00:16:03.442
there's likely a clinical trial center
part of Endeavor Health that, you know,

808e9326-1751-4154-a778-cefeca685554/77-0
00:16:01.784 --> 00:16:01.944
Mm.

808e9326-1751-4154-a778-cefeca685554/79-3
00:16:03.442 --> 00:16:08.382
you can go to to get your labs or to get
you be seen evaluated, et cetera.

808e9326-1751-4154-a778-cefeca685554/78-0
00:16:06.104 --> 00:16:06.384
And.

808e9326-1751-4154-a778-cefeca685554/79-4
00:16:08.382 --> 00:16:09.304
And certainly,

808e9326-1751-4154-a778-cefeca685554/81-0
00:16:09.464 --> 00:16:13.311
Most of the trials will be offered,
you know, throughout, you know,

808e9326-1751-4154-a778-cefeca685554/81-1
00:16:13.311 --> 00:16:16.932
the entire system. So again,
that improves access just based on

808e9326-1751-4154-a778-cefeca685554/81-2
00:16:16.932 --> 00:16:20.270
location, et cetera.
But then we're also forward thinking.

808e9326-1751-4154-a778-cefeca685554/80-0
00:16:19.704 --> 00:16:19.904
Yeah.

808e9326-1751-4154-a778-cefeca685554/81-3
00:16:20.270 --> 00:16:23.438
And as you said,
is that our goal is that it's not only

808e9326-1751-4154-a778-cefeca685554/81-4
00:16:23.438 --> 00:16:27.512
just serving the lives that we see
immediately in the Chicagoland area,

808e9326-1751-4154-a778-cefeca685554/81-5
00:16:27.512 --> 00:16:30.624
but it's how do we serve a greater good
throughout the

808e9326-1751-4154-a778-cefeca685554/82-0
00:16:31.944 --> 00:16:36.267
the country as well.
And so if patients are, you know,

808e9326-1751-4154-a778-cefeca685554/82-1
00:16:36.267 --> 00:16:41.927
identified and you're on the East Coast,
so in Maryland or in New York,

808e9326-1751-4154-a778-cefeca685554/82-2
00:16:41.927 --> 00:16:48.452
and they want to be part of a trial here,
is that possible? And the answer is yes,

808e9326-1751-4154-a778-cefeca685554/82-3
00:16:48.452 --> 00:16:54.584
because in the era of telemedicine,
in the era of so much virtual healthcare,

808e9326-1751-4154-a778-cefeca685554/83-0
00:16:54.904 --> 00:17:00.895
that a lot of things that we can do can
be done as certainly as a follow-up or,

808e9326-1751-4154-a778-cefeca685554/83-1
00:17:00.895 --> 00:17:07.035
you know, at great distances away. Now,
the exception for that would be if you're

808e9326-1751-4154-a778-cefeca685554/83-2
00:17:07.035 --> 00:17:12.278
getting a drug delivered or something
that actually requires multiple

808e9326-1751-4154-a778-cefeca685554/83-3
00:17:12.278 --> 00:17:14.824
interventions and stuff like that.

808e9326-1751-4154-a778-cefeca685554/85-0
00:17:14.904 --> 00:17:18.257
A lot of times,
you have to come in town for that,

808e9326-1751-4154-a778-cefeca685554/85-1
00:17:18.257 --> 00:17:23.714
and there's no way to overcome that part.
But certainly, if it's a national trial,

808e9326-1751-4154-a778-cefeca685554/84-0
00:17:20.424 --> 00:17:20.904
Mmh.

808e9326-1751-4154-a778-cefeca685554/85-2
00:17:23.714 --> 00:17:27.133
we'll help identify a center that may be,
you know,

808e9326-1751-4154-a778-cefeca685554/85-3
00:17:27.133 --> 00:17:31.144
closer that can give you that in that
setting, trial center.

808e9326-1751-4154-a778-cefeca685554/86-0
00:17:31.944 --> 00:17:37.982
So if you were in a patient in New York
and you were identified and needed to

808e9326-1751-4154-a778-cefeca685554/86-1
00:17:37.982 --> 00:17:41.465
participate in an Endeavor trial in
Chicago,

808e9326-1751-4154-a778-cefeca685554/86-2
00:17:41.465 --> 00:17:47.580
would it be possible for that patient in
New York to have labs or imaging done

808e9326-1751-4154-a778-cefeca685554/86-3
00:17:47.580 --> 00:17:51.064
remotely and then have those samples
shipped

808e9326-1751-4154-a778-cefeca685554/87-0
00:17:51.224 --> 00:17:52.504
to Chicago.

808e9326-1751-4154-a778-cefeca685554/89-0
00:17:53.504 --> 00:17:58.444
So it's not a uniform yes,
because certain clinical trials depends

808e9326-1751-4154-a778-cefeca685554/89-1
00:17:58.444 --> 00:18:03.532
on the sponsor or the type of trial
you're doing, may not permit it.

808e9326-1751-4154-a778-cefeca685554/88-0
00:18:01.384 --> 00:18:01.864
Mhm.

808e9326-1751-4154-a778-cefeca685554/89-2
00:18:03.532 --> 00:18:08.251
But for the most part,
that scenario that you described is very

808e9326-1751-4154-a778-cefeca685554/89-3
00:18:08.251 --> 00:18:11.864
possible and frequently done at Endeavor
Health.

808e9326-1751-4154-a778-cefeca685554/92-0
00:18:12.104 --> 00:18:15.082
So again,
our goal is to provide that care no

808e9326-1751-4154-a778-cefeca685554/92-1
00:18:15.082 --> 00:18:20.586
matter where you are and that top quality.
So if it's easier and you so happen to be

808e9326-1751-4154-a778-cefeca685554/90-0
00:18:16.504 --> 00:18:17.024
Mhm.

808e9326-1751-4154-a778-cefeca685554/92-2
00:18:20.586 --> 00:18:23.823
in New York,
you can certainly get local imaging,

808e9326-1751-4154-a778-cefeca685554/92-3
00:18:23.823 --> 00:18:27.643
local labs done,
send over that and overcome that for most

808e9326-1751-4154-a778-cefeca685554/92-4
00:18:27.643 --> 00:18:31.464
trials. And again,
some of this is just dependent on that.

808e9326-1751-4154-a778-cefeca685554/91-0
00:18:29.464 --> 00:18:30.024
Tong.

808e9326-1751-4154-a778-cefeca685554/93-0
00:18:32.504 --> 00:18:37.367
How much of an outlier is Endeavor
compared to other health systems across

808e9326-1751-4154-a778-cefeca685554/93-1
00:18:37.367 --> 00:18:41.648
the country is becoming a,
it sounds like Endeavor is positioning

808e9326-1751-4154-a778-cefeca685554/93-2
00:18:41.648 --> 00:18:46.576
itself to at least try to become a
national destination center for clinical

808e9326-1751-4154-a778-cefeca685554/93-3
00:18:46.576 --> 00:18:50.467
trial excellence.
Is this kind of common or uncommon as you

808e9326-1751-4154-a778-cefeca685554/93-4
00:18:50.467 --> 00:18:52.024
try to gain market share

808e9326-1751-4154-a778-cefeca685554/94-0
00:18:52.824 --> 00:18:57.704
far beyond the immediate kind of
geographic area of your health system.

808e9326-1751-4154-a778-cefeca685554/95-0
00:18:58.624 --> 00:19:02.471
So, I think it is an uncommon goal.
I mean,

808e9326-1751-4154-a778-cefeca685554/95-1
00:19:02.471 --> 00:19:08.504
I think a lot of places in the country,
you know, are really just...

808e9326-1751-4154-a778-cefeca685554/96-0
00:19:09.704 --> 00:19:14.406
They're not as interested in, you know,
providing cutting edge care.

808e9326-1751-4154-a778-cefeca685554/96-1
00:19:14.406 --> 00:19:19.722
They're kind of happy with the standard
and they will adopt practices as they

808e9326-1751-4154-a778-cefeca685554/96-2
00:19:19.722 --> 00:19:24.016
become more routine.
I think our positioning is we really want

808e9326-1751-4154-a778-cefeca685554/96-3
00:19:24.016 --> 00:19:29.263
to offer really the cutting edge,
outstanding, you know, care on top of the,

808e9326-1751-4154-a778-cefeca685554/96-4
00:19:29.263 --> 00:19:32.467
you know,
on top of the great care that people

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00:19:32.467 --> 00:19:32.944
already

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00:19:33.224 --> 00:19:36.908
receive here.
And so I think that as a primary

808e9326-1751-4154-a778-cefeca685554/98-1
00:19:36.908 --> 00:19:41.377
motivation, it distinguishes us.
I think our nimbleness,

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00:19:41.377 --> 00:19:46.394
and one of the things I didn't really
talk about was, you know,

808e9326-1751-4154-a778-cefeca685554/98-3
00:19:46.394 --> 00:19:52.744
what things are we doing to facilitate
the process? One of the things that we do

808e9326-1751-4154-a778-cefeca685554/97-0
00:19:50.664 --> 00:19:51.144
Mhm.

808e9326-1751-4154-a778-cefeca685554/99-0
00:19:52.904 --> 00:19:58.275
in research, no matter where you are,
is we kind of hurt ourselves because you

808e9326-1751-4154-a778-cefeca685554/99-1
00:19:58.275 --> 00:20:03.102
want a trial. Let's say I'm at, you know,
the classic academic center.

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00:20:03.102 --> 00:20:07.861
It usually takes over a year to get a
clinical trial approved at your

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00:20:07.861 --> 00:20:12.960
institution. And that's, you know,
through the institutional review board,

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00:20:12.960 --> 00:20:14.184
the study reviews.

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00:20:14.344 --> 00:20:17.729
before that's actually up and going.
And by that time,

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00:20:17.729 --> 00:20:20.438
a lot of people have already passed you
up.

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00:20:20.438 --> 00:20:25.055
And a lot of times you've already missed
a lot of patients that could have

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00:20:25.055 --> 00:20:29.549
benefited from that. So as an example,
our goal is that by the time you,

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00:20:29.549 --> 00:20:33.304
a physician investigator says, hey,
I want to start a study,

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00:20:33.704 --> 00:20:38.478
We want to have that up and rolling
within 30 days. It is,

808e9326-1751-4154-a778-cefeca685554/102-1
00:20:38.478 --> 00:20:43.737
it's an aggressive goal.
I think if we want to become really the

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00:20:43.737 --> 00:20:47.864
leading trial and, you know,
translational science

808e9326-1751-4154-a778-cefeca685554/103-0
00:20:49.704 --> 00:20:53.339
destination in the country.
That's what we're going to really have to

808e9326-1751-4154-a778-cefeca685554/103-1
00:20:53.339 --> 00:20:56.144
do to be looked at and viewed as a
preferred partner.

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00:20:57.144 --> 00:21:00.521
So, Brian,
we are approaching the end of this

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00:21:00.521 --> 00:21:04.413
podcast episode.
I'd like to ask you a kind of broad

808e9326-1751-4154-a778-cefeca685554/104-2
00:21:04.413 --> 00:21:08.084
concluding question. Endeavor wants to,
you know,

808e9326-1751-4154-a778-cefeca685554/104-3
00:21:08.084 --> 00:21:12.930
start a clinical trial and have it up and
rolling within 30 days.

808e9326-1751-4154-a778-cefeca685554/104-4
00:21:12.930 --> 00:21:18.584
You potentially have an entire nation
full of possible future clinical trial

808e9326-1751-4154-a778-cefeca685554/106-0
00:21:18.904 --> 00:21:24.701
participants who may be getting lab
specimens or imaging drawn or done

808e9326-1751-4154-a778-cefeca685554/106-1
00:21:24.701 --> 00:21:30.417
remotely across the United States from
non-endeavor health providers.

808e9326-1751-4154-a778-cefeca685554/106-2
00:21:30.417 --> 00:21:36.786
You're having lots of different data
sources and a very ambitious timeline to

808e9326-1751-4154-a778-cefeca685554/106-3
00:21:36.786 --> 00:21:38.664
reconcile all this data

808e9326-1751-4154-a778-cefeca685554/107-0
00:21:39.144 --> 00:21:44.063
From a data perspective, you know,
what advice do you give to other health

808e9326-1751-4154-a778-cefeca685554/107-1
00:21:44.063 --> 00:21:48.720
systems or perhaps to yourself a few
years ago to overcome some of the

808e9326-1751-4154-a778-cefeca685554/107-2
00:21:48.720 --> 00:21:53.837
technical challenges or technological
challenges that are involved in getting

808e9326-1751-4154-a778-cefeca685554/107-3
00:21:53.837 --> 00:21:56.264
to where Endeavor Health wants to be?

808e9326-1751-4154-a778-cefeca685554/108-0
00:21:57.624 --> 00:22:00.862
I think it's partnering with several
things.

808e9326-1751-4154-a778-cefeca685554/108-1
00:22:00.862 --> 00:22:05.828
I think that having an internal
partnership with your IT department,

808e9326-1751-4154-a778-cefeca685554/108-2
00:22:05.828 --> 00:22:09.067
right?
All of this is going to be ultimately

808e9326-1751-4154-a778-cefeca685554/108-3
00:22:09.067 --> 00:22:12.737
based on getting that data in an
efficient manner.

808e9326-1751-4154-a778-cefeca685554/108-4
00:22:12.737 --> 00:22:16.264
I think parallel processing.
So we're so used to

808e9326-1751-4154-a778-cefeca685554/109-0
00:22:16.584 --> 00:22:21.239
going from A to B to C,
but we want ABC to be happening all

808e9326-1751-4154-a778-cefeca685554/109-1
00:22:21.239 --> 00:22:25.351
simultaneously,
becoming efficient in how we look at

808e9326-1751-4154-a778-cefeca685554/109-2
00:22:25.351 --> 00:22:31.170
trials and getting them up and rolling.
The IRB should be working with the

808e9326-1751-4154-a778-cefeca685554/109-3
00:22:31.170 --> 00:22:37.144
compliance, which should be working.
So it all has to happen simultaneously.

808e9326-1751-4154-a778-cefeca685554/111-0
00:22:37.464 --> 00:22:40.728
and most places are, you know,
still sequential.

808e9326-1751-4154-a778-cefeca685554/111-1
00:22:40.728 --> 00:22:45.925
I think when it comes to data, again,
a lot of this is going to depend on the

808e9326-1751-4154-a778-cefeca685554/110-0
00:22:41.264 --> 00:22:41.744
Mmh.

808e9326-1751-4154-a778-cefeca685554/111-2
00:22:45.925 --> 00:22:51.121
type of study, but as you're alluding to,
we just have that complexity to get

808e9326-1751-4154-a778-cefeca685554/111-3
00:22:51.121 --> 00:22:55.118
images in, et cetera.
So establishing those secure sites to

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00:22:55.118 --> 00:22:56.984
protect patient information,

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00:22:57.304 --> 00:23:03.086
to get that information in a reliable way
that you can trust and that can be then

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00:23:03.086 --> 00:23:08.867
included in the studies is also important.
And that sounds simple, right? I mean,

808e9326-1751-4154-a778-cefeca685554/112-2
00:23:08.867 --> 00:23:12.534
these concepts are like, you got data,
you want it,

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00:23:12.534 --> 00:23:16.624
and we've got to bring that in.
But there's a lot of work

808e9326-1751-4154-a778-cefeca685554/113-0
00:23:16.904 --> 00:23:23.598
that has to go on behind the scenes and
foundation to make that happen. But again,

808e9326-1751-4154-a778-cefeca685554/113-1
00:23:23.598 --> 00:23:29.002
because clinical trials,
we don't want to increase risk to patient

808e9326-1751-4154-a778-cefeca685554/113-2
00:23:29.002 --> 00:23:33.761
and we want to limit that risk as much as
we possibly can.

808e9326-1751-4154-a778-cefeca685554/113-3
00:23:33.761 --> 00:23:36.584
And so one of those risks cannot be

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00:23:36.704 --> 00:23:42.091
that we leak that information outside or
that it was compromised in some fashion.

808e9326-1751-4154-a778-cefeca685554/114-1
00:23:42.091 --> 00:23:45.704
So having those necessary guardrails in
place is also.

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00:23:47.144 --> 00:23:49.330
Brian,
thank you so much for joining us today.

808e9326-1751-4154-a778-cefeca685554/115-1
00:23:49.330 --> 00:23:51.144
I really appreciate your participation.

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00:23:51.544 --> 00:23:52.584
Thank you, thank you.

808e9326-1751-4154-a778-cefeca685554/117-0
00:23:52.984 --> 00:23:56.662
And for our listeners,
this has been Brian Helfand at Endeavor

808e9326-1751-4154-a778-cefeca685554/117-1
00:23:56.662 --> 00:23:59.464
Health,
the Associate Chief Scientific Officer.