Cathal Friel & Mo Khan, the newly appointed CEO of Open Orphan, discuss the new board structure

Cathal Friel, Executive Chairman & Mo Khan, the newly appointed CEO of Open Orphan #ORPH discuss the new board structure.

Highlights

Executive Chairman, Cathal Friel will continue in his role under the new management structure.

On 13 October 2021, the Company disclosed that Mo was appointed as an Independent Non-Executive Director of Open Orphan and that he would Chair both the Audit and Risk, and Nomination Committees. With Mo stepping into an executive role, the Company will look to fill the vacant Independent Non-Executive position and associated committee positions within the next 6 months. In the interim Mo will remain on both the Audit and Risk, and Nomination Committees however he will step down as Chair with immediate effect. He will also step down from the Remuneration Committee with immediate effect. Elaine Sullivan, as Independent Non-Executive Director, will take on the Chair position for the Audit & Risk Committee in the interim and for the Nomination Committee on a full-time basis.

Mo is a business leader and customer-focused CRO executive with over 25 years of global clinical research experience across clinical operations, project management, business development and executive management functions. He previously worked at Pharm-Olam International, a global CRO, for 19 years from 2000-2019. Mo worked across a variety of senior positions including Executive Vice President of Clinical Development and Global Director of Clinical Operations. Mo was a key leader in driving the expansion and growth of the company from a small niche Eastern European CRO to a global player with offices across all continents. Laterally, he led global business development at Pharm-Olam resulting in significant growth and a successful sale in 2017, delivering substantial returns to its shareholders. Prior to this he worked at Innovex and Quintiles CRO (IQVIA).

About Open Orphan plc

Open Orphan plc (London and Euronext: ORPH) is a rapidly growing contract research company that is a world leader in testing vaccines and antivirals using human challenge clinical trials. The Company provides services to Big Pharma, biotech, and government/public health organisations.

Open Orphan runs challenge studies in London from both its 19-bedroom Whitechapel quarantine clinic and its state-of-the-art 24-bedroom QMB clinic with its highly specialised on-site virology and immunology laboratory. The Company has a leading portfolio of human challenge study models for infectious and respiratory diseases and is developing a number of new models. There has been significant growth of the infectious disease market, which is estimated to grow to in excess of $250bn by 2025. The Group is focused on refreshing its existing challenge models and develop new models, such as Malaria, to address the dramatic growth potential of the global infectious disease market.

Building upon its many years of challenge studies and virology research, the Company is developing an in-depth database of infectious disease progression data. Based on the Company's Disease in Motion® platform, this unique dataset includes clinical, immunological, virological, and digital (wearable) biomarkers. The Disease in Motion platform has many potential applications across a wide variety of end users including big technology, wearables, pharma, and biotech companies.

Open Orphan's Paris office has been providing biometry, data management and statistics to its many European pharmaceutical clients for over 20 years. For over 15 years, the Company's Netherlands office has been providing drug development consultancy and services, including CMC (chemistry, manufacturing, and controls), PK and medical writing, to a broad range of European clients. Both offices are now also fully integrated with the London office and working on challenge study contracts as well as supporting third party trial contracts.