The ARISE Study and Using DMTs in RIS

Episode 83,   Feb 24, 2023, 11:00 AM

Welcome to the NeurologyLive® Mind Moments® podcast. Tune in to hear leaders in neurology sound off on topics that impact your clinical practice.

In this episode, we spoke with Darin Okuda, MD, director of Neuroinnovation and Multiple Sclerosis & Neuroimmunology Imaging Program at UT Southwestern Medical Center. He spoke about the phase 2 ARISE study assessing dimethyl fumarate (Tecfidera; Biogen) in patients with radiologically isolated syndrome, the significance of the findings, next steps in validating this therapy, and more. 

Looking for more multiple sclerosis discussion? Check out the NeurologyLive® multiple sclerosis clinical focus page.

Episode Breakdown:
  • 1:20 – Overview of ARISE and conduct of study
  • 4:20 – Potential subgroup responders to dimethyl fumarate
  • 8:10 – Efforts to improve the detection of radiologically isolated syndrome
  • 10:05 – Neurology News Minute
  • 11:55 – Next steps of research following ARISE
  • 16:50 – Closing thoughts on significance of the study

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The stories featured in this week's Neurology News Minute, which will give you quick updates on the following developments in neurology, are further detailed here:


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REFERENCE
Okuda DT, Kantarci O, Lebrun-Frenay C, et al. Dimethyl fumarate delays multiple sclerosis radiologically isolated syndrome. Ann Neurol. 2023;93(3):604-614. doi:10.1002/ana.26555