Ospemifene: A Pill a Day to Keep Dryness Away

Season 2, Episode 74,   Apr 27, 2023, 12:30 AM

Today’s topic is based on question that come in through my website. 

“Some of us have difficulty tolerating the vaginal creams and ring. The estrogen creams cause my urethra to immediately begin spasming! My doctor has mentioned this ospemifene as a possibility, but I’d like to hear some details on it from your perspective.”
For those who would rather put a pill in their mouth than in their vagina, ospemifene is a non-estrogen option to alleviate vaginal dryness and painful intercourse.

  In this episode, I discuss: 
  • How ospemifene works
  • SERMS (selective estrogen receptor modulators) 
  • The impact of ospemifene on bones, bladder, and breast tissue
  • Why the FDA has a breast cancer warning on the label
  • Who should not use ospemifene
  • Side effects
To ask a question, go to
 DrStreicher/com/podcast#ask
Hit the microphone icon and start talking! 


More Information
Episode 3: What's Up Down There? Genital Dryness & Misbehaving Bladders 
Episode 4: Is Your Lubricant Helping or Hurting Your Vagina?
Episode 5: Vaginal Estrogen- Rings, Creams, and Other Things 
Episode 11: Vaginal Estrogen is Not Poison
Episode 27:  Using Vaginal Estrogen but Sex Still Hurts Like Hell 
Episode 61 Boning Up on Bones: Part 2 with Dr. Kristi Tough DeSapri 
Episode 63 DHEA-An Estrogen Alternative for Vaginal Dryness 

 Slip Sliding Away: Turning Back the Clock on Your Vagina-A gynecologist’s guide to eliminating post-menopause dryness and pain

Lauren Streicher, MD is a clinical professor of obstetrics and gynecology at Northwestern University’s Feinberg School of Medicine, and the founding medical director of the Northwestern Medicine Center for Sexual Medicine and Menopause. She is a certified menopause practitioner of the North American Menopause Society. 

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Dr. Streicher is the medical correspondent for Chicago’s top-rated news program, the WGN Morning News, and has been seen on The Today Show, Good Morning America, The Oprah Winfrey Show, CNN, NPR, Dr. Radio, Nightline, Fox and Friends, The Steve Harvey Show, CBS This Morning, ABC News Now, NBCNightlyNews,20/20, and World News Tonight. She is an expert source for many magazines and serves on the medical advisory board of The Kinsey Institute, Self Magazine, and Prevention Magazine. She writes a regular column for The Ethel by AARP and Prevention Magazine. 


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Books by Lauren Streicher, MD

 Slip Sliding Away: Turning Back the Clock on Your Vagina-A gynecologist’s guide to eliminating post-menopause dryness and pain

Hot Flash Hell: A Gynecologist's Guide to Turning Down the Heat

Sex Rx- Hormones, Health, and Your Best Sex Ever

The Essential Guide to Hysterectomy