Associated Brain Alterations & Future Suicide Ideation in Females with Mood Disorders

May 09, 2023, 11:05 AM

In this Papers Podcast, Lejla Colic and Dr. Hilary Blumberg discuss their co-authored JCPP Advances paper ‘Brain grey and white matter structural associations with future suicidal ideation and behaviors in adolescent and young adult females with mood disorders’.

DOI: 10.13056/acamh.23772

In this Papers Podcast, Lejla Colic and Dr. Hilary Blumberg discuss their co-authored JCPP Advances paper ‘Brain grey and white matter structural associations with future suicidal ideation and behaviors in adolescent and young adult females with mood disorders’ (https://doi.org/10.1002/jcv2.12118).

There is an overview of the paper, methodology, key findings, and implications for practice.

Discussion points include;

  • The age range included in the study.
  • The significance of females with future suicide ideation and behaviours having shown decreases in cortical thickness, as well as some other differences in brain regions observing emotional and behavioural regulation.
  • The importance of cortical thickness.
  • The origins of these neurobiological differences – are they genetic, environmental, developmental, or some combination of all of these?
  • The reason for focusing on young adult and adolescent females, and how these findings are relevant to males.
  • How this research can be translated into practice to better identify and support adolescents at risk of suicidal ideation and behaviours.
In this series, we speak to authors of papers published in one of ACAMH’s three journals. These are The Journal of Child Psychology and Psychiatry (JCPP); The Child and Adolescent Mental Health (CAMH) journal; and JCPP Advances.